Table 1.
Modulation of Ion transporters and channels involved in sodium and chloride absorption in IBD Patients.
| CD | UC | |
|---|---|---|
| NHE-3 | ⇓ (35, 54) |
⇓ (23, 35, 51, 52, 53, 54) |
| ENaC | ⇓ (23, 25, 35, 67, 68, 69, 70, 71) |
⇓ (23, 25, 35, 67, 68, 69, 70,71) |
| Na+/K+ATPase | ⇓ (68, 79, 80) |
⇓ (68, 69, 79, 80, 81) |
| DRA | ⇔ (110) |
⇓ (23, 52, 110, 109) |
⇑ increase, ⇓ decrease, ⇔ no effect, Number in parenthesis indicate citation number.
NHE1, NHE2 and NHE8 are not included in the table as the reports with respect to the changes in their function and/or expression in inflammation appears to be contradictory and requires further validation.