Table 2.
Participant Fasting 6 am Laboratory Measures
| Characteristic | T1D | Control | P Value |
|---|---|---|---|
| Leptin, ng/mL | 14.5 (9.7, 27.0) | 16.8 (7.4, 31.7) | 0.45 |
| Adiponectin, ng/mL | 9.1 (7.20, 13.40) | 8.3 (6.5, 11.1) | 0.37 |
| Cholesterol, mg/dL | 140 (126, 160) | 156 (134, 185) | 0.049 |
| HDL cholesterol, mg/dL | 46 ± 6 | 43 ± 9 | 0.25 |
| LDL cholesterol, mg/dL | 80 (65, 98) | 97 (76, 120) | 0.03 |
| Triglyceride, mg/dL | 73 (56, 102) | 94 (70, 136) | 0.08 |
| C-peptide, ng/mL | 0.05 (0.05, 0.10) | 1.70 (1.48, 2.73) | <0.0001 |
| AST, U/L | 27 (21, 34) | 30 (23, 43) | 0.31 |
| ALT, U/L | 16 (12, 25) | 22 (13, 27) | 0.30 |
| IL-6, mg/dL | 1.3 (1.3, 2.0) | 1.3 (1.3, 3.7) | 0.12 |
| WBC, 109cells/L | 6.4 (5.5, 7.7) | 6.1 (5.5, 7.5) | 0.60 |
| Platelets, 109cells/L | 247 (230, 280) | 243 (239, 274) | 0.82 |
| hs-CRP, mg/dL | 0.6 (0.2, 2.9) | 0.3 (0.2, 1.1) | 0.15 |
| HbA1c, % | 8.3 (7.3, 9.4) | 5.4 (5.2, 5.5) | <0.0001 |
Laboratory measures drawn after a 12-hour monitored inpatient fast are shown below for adolescents with and without T1D. Data are shown as mean ± SD or as median and the first and third quartiles.
Abbreviations: AST, aspartate aminotransferase; LDL, low-density lipoprotein; WBC, white blood cell count.