Table 1. Coefficients and their corresponding Hazard Ratios for overall survival based on predictive factors in 100 de novo AML samples.
| Variable | Coefficient | HR |
|---|---|---|
| Age | 0.017 | 1.018 |
| FLT3-ITD | 0.150 | 1.162 |
| KRAS | 0.009 | 1.010 |
| PTPN11 | 0.001 | 1.001 |
| DNAH8 | 0.093 | 1.097 |
| IGF1 | -0.026 | 0.975 |
| EZH2 | 0.263 | 1.301 |
| SMC3 | -0.009 | 0.991 |
| RAD21 | 0.386 | 1.471 |
| DNMT3A | 0.015 | 1.015 |
| IDH2 | 0.047 | 1.048 |
| TET2 | 0.179 | 1.196 |
| SIPA1L2 | -0.027 | 0.974 |
| GPR6 | 0.114 | 1.121 |
| PKD1L2 | 0.187 | 1.205 |
| RUNX1 | 0.060 | 1.062 |
| NPM1 | -0.134 | 0.874 |
| KCNU1 | -0.114 | 0.892 |
| FAM69B | 0.038 | 1.038 |
| NLRP5 | -0.164 | 0.848 |
| PCDHA7 | 0.511 | 1.667 |
| ZCCHC1 | -0.025 | 0.975 |
| CCNL2 | -0.014 | 0.986 |
| TP53 | 0.376 | 1.457 |
| WT1 | 0.165 | 1.179 |
| PIK3R | -0.123 | 0.884 |
| OTUD7A | 0.301 | 1.352 |