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. 2018 Oct 10;13(10):e0204288. doi: 10.1371/journal.pone.0204288

Fig 5. Dynasore protects cells against damage due to oxidative stress.

Fig 5

A) HCLE monolayer cultures plated in triplicate were either left unstressed or stressed with 10 mM tBHP. At the same time, a set of unstressed and stressed cultures were treated with Dynasore (40 uM). (An equal volume of the Dynasore diluent, DMSO, was added to untreated cultures.) After 2 hours, WST-1 and MTT assays were performed: *, p<0.05; **, P<0.01 (student t-test, n = 3).B) HCLE monolayer cultures plated in triplicate were either left unstressed or stressed with 10 mM tBHP. At the same time, a set of unstressed and stressed cultures were treated with Dynasore (40 uM). (An equal volume of the Dynasore diluent, DMSO, was added to untreated cultures.) After 3 hours, cells were stained with trypan blue dye and imaged under white light. Representative images are shown from each triplicate set: *, p<0.01 (student t-test, n = 3).