Table 3. Quantitative outcomes of tuberculosis patient support interventions in low incidence countries described in studies not allowing for comparisons to a control group.
Source | Intervention | Target group* | N | Outcome | N outcome |
---|---|---|---|---|---|
Charokopos et al., 2013 [49], Greece | Modified DOT | Newly diagnosed TB patients | 54 | Treatment completion | 11 (85%) |
Craig et al., 2008 [43], UK | TB link worker | Adult TB/LTBI patients referred on the basis of social need to TBLW | 90 | Treatment completion | 70 (78%) |
Escudero et al., 2006 [40], Spain | In-patient DOT | HIV-negative MDR-TB patients | 25 | Treatment completion | 21 (84%) |
Ferrer et al., 2010 [41], USA | DOT by social worker | MDR-TB patients | 46 | Treatment completion | 30 (65%) |
Garfein et al., 2015 [44], USA | VOT via uploading videos via a smart phone app + daily text message reminders | Adult newly diagnosed DS TB patients treated under VOT | 41 |
Treatment adherence [average doses missed] | 2.7±7 |
Treatment adherence [observed doses/ expected doses] | 93% | ||||
Jit et al., 2011 [51], UK | Find and Treat Service | Hard to reach individuals with active PTB | 188 | Treatment completion# | 61% |
Luzzati et al., 2011 [45], Italy | In-patient DOT | Adult patients admitted to referral TB Centre for high risk | 122 | Treatment adherence [not defined] | 96% |
Mejuto et al., 2010 [38], Spain | DOT at various locations | TB patients who received DOTS treatment | 253 | Treatment completion | 213 (82%) |
Pursnani et al., 2014 [50], USA | Out-patient DOT | Patients on out-patient DOT | 70 | Treatment completion | 62 (89%) |
*descriptions of the target groups can be found in S2 Appendix
#Based on modelling data
DOT: Directly Observed Treatment, N: number, PTB: Pulmonary TB, TB: Tuberculosis, VOT: Video observed treatment