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. Author manuscript; available in PMC: 2018 Oct 10.
Published in final edited form as: Cell Rep. 2018 Aug 21;24(8):2042–2050.e6. doi: 10.1016/j.celrep.2018.07.054

Figure 3. The Contribution of the Offset of ON and OFF Subregions of the Thalamic Excitation to Its Orientation Preference.

Figure 3.

The ON and OFF subfields of the thalamic inputs were estimated by presenting spots at different locations to the model network as in Lien and Scanziani (2013) (see STAR Methods).

(A) Top panels: ON (red) and OFF (green) subfields of the thalamic excitation for four example neurons. Dark spots: Center of mass of the subfields. The solid line indicates the axis of the offset of the two centers of mass. Receptive fields based on the summed ON and OFF thalamic inputs are shown on the right. The scale bar on the right applies to all receptive fields. Bottom panels: Tuning curves of the thalamic excitation for these neurons. The SF of the drifting grating is 0.03 cyc/deg. Vertical dashed line indicates the orientation of the offset axis (0 corresponds to an horizontal axis). Offset amplitude and orientation and preference of the thalamic excitation are as follows: E14493, 11.4°, 166.1°, 160.3°; E14847, 4.7°, 18.2°, 31.1°; E14664, 3.9°, 111.4°, 80.7°; E15022, 2.8°, 20.6°, 88.0°.

(B) Offset distribution across neurons (n = 361;neurons are at the center of the network, see STAR Methods). Mean offset: 4.1°.

(C) Orientation preference of the thalamic input conductance (drifting grating with 0.03 cyc/deg) versus orientation from the offset axis (perpendicular to the offset axis) for all neurons with an offset larger than 4 (n = 170). The CC is 0.24.