Table 1.
Topical Beta-blockers Commonly Used for Glaucoma Treatment
| Generic Name | Trade Name | Receptors | Concentration | Dose | Clinical Pearl |
|---|---|---|---|---|---|
| Timolol | Timoptic® | Beta 1 and 2 | 0.25%, 0.50% | BID | Former gold standard |
| Timolol | Timpotic XE® | Beta 1 and 2 | 0.25%, 0.50% | QD | XE is gel form |
| Timolol | Betimol® | Beta 1 and 2 | 0.25%, 0.50% | BID | Hemihydrate |
| Betaxolol | Betoptic® | Beta 1 | 0.50% | BID | Betaxon (newer) |
| Betaxolol | Betoptic S® | Beta 1 | 0.25% (susp) | BID | More selective |
| Levobunolol | Betagan® | Beta 1 and 2 | 0.25%, 0.50% | BID or QD | Longest half-life |
| Meti-pranolol | Optipranolol® | Beta 1 and 2 | 0.30% | BID | Rare uveitis risk |
| Carteolol | Ocupress® | Beta 1 and 2 | 1.0% | BID | Intrinsic sympathomimetic activity |