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. Author manuscript; available in PMC: 2018 Oct 10.
Published in final edited form as: Biochem Pharmacol. 2017 Apr 19;137:93–106. doi: 10.1016/j.bcp.2017.04.017

Table 5.

Correlation between hepatic miRNA transcript levels and glucuronidation activities of various human UGT1A isoforms measured in matched microsomal and RNA samples isolated from a human liver bank (n=25). Shown are the Spearman correlation coefficients (Rho) and the associated P values.

miRNA UGT1A1 activity UGT1A4 activity UGT1A6 activity UGT1A9 activity
Rho p Rho p Rho p Rho p
miR-21–3p −0.376 0.07 −0.150 0.475 −0.408 0.048 −0.295 0.16
miR-103b −0.132 0.538 −0.169 0.43 0.077 0.719 −0.096 0.653
miR-141–3p −0.073 0.734 −0.1 0.639 −0.36 0.0839 −0.148 0.49
miR-200a-3p −0.376 0.069 −0.153 0.475 −0.408 0.048 −0.296 0.16
miR-376b-3p −0.151 0.48 −0.33 0.114 −0.138 0.52 0.053 0.802