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Plasma concentration at trough (mean ± SE)–time profile during and following 12-weeks of treatment with cariprazine 6 mg/day.
Notes: Reproduced from the product label.10 DDCAR is the predominant circulating moiety, representing about 70% of the total exposure. When treatment is discontinued, DDCAR concentrations persist longer than for cariprazine or DCAR.
Abbreviations: CAR, cariprazine; DDCAR, didesmethyl-cariprazine; total CAR, summed concentration of cariprazine, DCAR, and DDCAR.
