Fig. 7.

Patients with breast cancer showing low CHIP E3 ligase expression have poor survival probability. a Overall, relapse free, distant metastasis and post-progression survival were analyzed with CHIP expression level using Kaplan–Meier plot analysis. b CHIP and OCT4 expression levels of both malignant (T) and normal (N) tissues were detected using western blotting using western blot. β-Actin was used a normalization control. The data are presented as mean ± SD (n = 5). We also quantitated the protein changes of CHIP and OCT4, and venn diagram was presented (right). Significant differences are indicated by an asterisk (*p < 0.05, **p < 0.01); p values were calculated using Student’s t test