Tractography-based classification results and the tract strength comparisons among nonsmokers, abstainers and lapsers. a Tractography-based classification results of left striatum with frontal cortex (dorsolateral prefrontal cortex (dlPFC), medial orbitofrontal cortex (mOFC), inferior frontal gyrus (IFG), ventral lateral PFC (vlPFC)) in smokers. For display purposes, each striatal part was then transformed to standard MNI (Montreal Neurological Institute) space and overlapped across the majority of subjects (defined as 60% here). b The tract strength comparisons of left striatum-dlPFC among the three groups. c The tract strength comparisons of left striatum with mOFC, vlPFC, IFG and posterior cingulate cortex (PCC) among the three groups (*p < 0.05 uncorrected, **p < 0.0025, Bonferroni correction)