Fig. 5.

No overlapping genes between CeA and OFC during incubation of Meth craving. a Table shows the odds ratio, Jaccard Indexm, and p-value for Fisher’s exact test for enrichment of DEGs between CeA and OFC on withdrawal day 2 and withdrawal day 35, respectively. N.S., nonsignificant. b RRHO map compares all expressed genes between CeA and OFC on withdrawal day 2 (left) and 35 (right). Each pixel represents the overlap between downregulated and upregulated genes in a transcriptome-wide threshold-free manner on the two withdrawal days. The significance of overlap (-log₁₀(p-value) of a hypergeometric test) is color coded, with warmer colors indicated increasing significance