Fig. 5. Increased miR-96 expression and reduced ABCE1 expression are correlated with lower tumor grade, preferable intrinsic tumor subtype, and longer survival in humans.

Clinical data of 1,262 breast cancer patients, of which expression levels of miR-96 and ABCE1 were available, were obtained from the METABRIC database. a miR-96 expression was inversely correlated with tumor grade and b basal type breast cancer. c Kaplan–Meier survival analysis demonstrates longer overall survival of patients with breast tumors that highly express miR-96. d ABCE1 expression was correlated with higher tumor grade and e basal type breast cancer. f Kaplan–Meier survival analysis demonstrates longer overall survival of patients with breast tumors that lowly express ABCE1. Data are presented as mean +/- SEM. **p < 0.01, ***p < 0.001, ****p < 0.0001