Table 2.
Univariate and multivariate analysis for OS of CRC patients
| Variables | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p Value | HR | 95% CI | p Value | |
| Gender (male, female) | 2.599 | 0.838–8.066 | 0.089 | |||
| Age (>63, ≤63), years | 0.762 | 0.277–2.098 | 0.599 | |||
| Tumor location (colon, rectum) | 0.598 | 0.224–1.598 | 0.306 | |||
| TNM stage (III+IV, I+II) | 4.44 | 1.42–13.89 | 0.01 | 3.87 | 1.13–13.33 | 0.031 |
| Histologic grade (3, 1+2) | 4.67 | 1.06–20.4 | 0.042 | 5.35 | 1.09–26.32 | 0.038 |
| Lymphatic metastasis (N1+N2, N0) | 2.81 | 1.04–7.58 | 0.041 | 1.93 | 0.65–5.68 | 0.235 |
| Distant metastasis (M1, M0) | 5.92 | 1.99–17.54 | 0.001 | 2.78 | 0.76–10.1 | 0.121 |
| Tumor size (>4 cm, ≤4 cm) | 4.062 | 0.92–17.94 | 0.064 | 4.51 | 0.89–22.67 | 0.067 |
| miR-486-5p expression (high, low) | 0.306 | 0.11–0.83 | 0.019 | 0.68 | 0.21–2.22 | 0.523 |