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. 2018 Oct 4;9:1390. doi: 10.3389/fphys.2018.01390

Table 4.

Summary of heart rate variability measures available in the PhysioZoo software.

Measures Units Definition
Time domain
AVNN [ms] Average NN interval duration
SDNN [ms] Standard deviation of NN interval duration
RMSSD [ms] The square root of the mean of the sum of the squares of differences between adjacent NN intervals
pNNxx [%] Percent of NN interval differences greater than xx milliseconds
SEM [ms] Standard error of the mean NN interval
PIP [%] Percentage of inflection points in the NN interval time series
IALS [n.u] Inverse average length of the acceleration/deceleration segments
PSS [%] Percentage of short segments
PAS [%] The percentage of NN intervals in alternation segments
Frequency
Total power [ms2] Total power
VLF [ms2] Power in the very low frequency band
LF [ms2] Power in the low frequency band
HF [ms2] Power in the high frequency band
VLF norm [%] Low frequency power in normalized units LF/(Total power) × 100
LF norm [%] Low frequency power in normalized units LF/(Total power – VLF) × 100
HF norm [%] High frequency power in normalized units HF/(Total power – VLF) × 100
LF/HF [n.u] Low frequency band to high frequency band power ratio (LF/HF)
LF peak [Hz] Peak frequency in the low frequency band
HF peak [Hz] Peak frequency in the high frequency band
β [n.u] Slope of the linear interpolation of the spectrum in a log-log scale for frequencies below the upper bound of the VLF band
Non-linear
SampEn [n.u] Sample entropy Richman and Moorman, 2000
SD1 [ms] NN interval standard deviation along the perpendicular to the line-of-identity
SD2 [ms] NN interval standard deviation along the line-of-identity
α1 [n.u] DFA low-scale slope Peng et al., 1995
α2 [n.u] DFA high-scale slope

VLF, very low frequency; LF, low frequency; HF, high frequency; DFA, detrended fluctuation analysis; NN, interval between normal beats. Note that the normalization factor for the VLF norm measure (Total power) is different from the LF norm and HF norm ones (Total power-VLF). This is because the LF norm and HF norm measures were defined as such in the HRV standard. In the software we provide the option to change the normalization method to make it the same for all three frequency measures, i.e., divided by the total power.