Table 4.

Risk of hypothyroidism and thyroid autoimmunity among obese individuals compared with individuals with normal weight.

Thyroid dysfunction	Obese individuals	Normal weight	Crude OR		Adjusted OR*
			OR (95%CI)	P	OR (95%CI)	P
Total	N = 397	N = 1,366
Hypothyroidism#	55 (13.9%)	170 (12.4%)	1.13 (0.82–1.57)	0.46	1.25 (0.86–1.80)	0.24
SCH	53 (13.3%)	157 (11.5%)	1.19 (0.85–1.66)	0.32	1.31 (0.90–1.91)	0.16
TAI	49 (12.3%)	181 (13.3%)	0.92 (0.66–1.29)	0.64	1.11 (0.76–1.61)	0.60
TPOAb positivity	38 (9.6%)	114 (8.3%)	1.03 (0.71–1.51)	0.87	1.24 (0.81–1.91)	0.32
TGAb positivity	42 (10.6%)	148 (10.8%)	0.90 (0.63–1.30)	0.58	1.29 (0.86–1.94)	0.22
Men	N = 252	N = 540
Hypothyroidism#	22 (8.7%)	49 (%)	0.96 (0.57–1.62)	0.87	1.01 (0.56–1.80)	0.98
SCH	21 (8.3%)	47 (9.1%)	0.95 (0.56–1.63)	0.86	1.01 (0.56–1.83)	0.97
TAI	22 (8.7%)	34 (6.3%)	1.42 (0.81–2.49)	0.21	1.27 (0.68–2.35)	0.45
TPOAb positivity	16 (6.3%)	19 (3.5%)	1.52 (0.79–2.94)	0.21	1.30 (0.63–2.68)	0.48
TGAb positivity	17 (6.7%)	22 (4.1%)	1.56 (0.82–2.95)	0.18	1.54 (0.75–3.19)	0.24
Women	N = 145	N = 826
Hypothyroidism#	33 (22.7%)	121 (14.6%)	1.72 (1.11–2.65)	0.015	1.50 (0.93–2.42)	0.09
SCH	32 (22.1%)	110 (13.3%)	1.84 (1.19–2.86)	0.007	1.63 (1.00–2.65)	0.048
TAI	27 (18.6%)	147 (17.8%)	1.06 (0.67–1.66)	0.81	1.01 (0.62–1.65)	0.96
TPOAb positivity	22 (15.2%)	95 (11.5%)	1.24 (0.75–2.04)	0.39	1.16 (0.68–2.00)	0.58
TGAb positivity	25 (17.2%)	126 (15.3%)	1.08 (0.67–1.72)	0.76	1.18 (0.71–1.95)	0.52

^*Confounding factors in the multiple logistic regression analysis included age, sex, smoking, diabetes, hypertension, salt type and urinary iodine concentration.

^#Hypothyroidism included SCH and overt hypothyroidism. OR, odds ratio; 95%CI, 95% confidence interval. Bold values were statistically significant outcomes.