Table 1.
Remodelling markers | SAL | LPS | SAL-antiIL17 | LPS-antiIL17 |
---|---|---|---|---|
Collagen fibers (%) | 12.35 ± 1.01 | 23.90 ± 2.67 * | 11.55 ± 0.92 | 9.65 ± 0.37 */** |
Actin (%) | 17.92 ± 1.09 | 27.77 ± 2.38 * | 18.75 ± 2.46 | 9.14 ± 1.91*/** |
MMP-9 (cells/104μm2) | 2.70 ± 0.46 | 13.10 ± 0.80 * | 1.89 ± 0.38 | 5.88 ± 0.46 */** |
MMP-12 (cells/104μm2) | 0.32 ± 0.06 | 4.00 ± 0.22 * | 0.32 ± 0.09 | 0.26 ± 0.11** |
TIMP-1 (cells/104μm2) | 1.11 ± 0.18 | 8.42 ± 0.95 * | 1.01 ± 0.25 | 4.59 ± 0.52 */** |
TGF-β (cells/104μm2) | 1.65 ± 0.23 | 6.24 ± 0.80 * | 1.66 ± 0.25 | 1.71 ± 0.25** |
Collagen fiber and actin are expressed as percentage and MMP-9, MMP-12, TIMP-1 and TGF-β are expressed as the number of positive cells/104μm2.
P < 0.05, compared to the SAL and SAL-antiIL17 groups;
P < 0.05, compared to the LPS group.