Table 1.
Characteristics of cancer patients who received IV-tPA vs. never cancer who received IV-tPA.
| CS & IV-tPA (n = 5) | NCS & IV-tPA (n = 261) | P | |
|---|---|---|---|
| Male, n (%) | 4 (80.0) | 164 (62.8) | 0.4 |
| Female | 1 (20.0) | 97 (37.2) | |
| Time from ictus to admission | 73.1 (45.0–123.8) | 90 (59.1–135.0) | 0.5 |
| Mean age (SD) | 68.0 (10.4) | 68.7 (14.9) | 0.9 |
| Median NIHSS, arrival (IQR) | 9 (8–14) | 7 (4–15) | 0.9 |
| Median NIHSS, discharge (IQR) | 11 (0–19) | 3 (0–9) | 0.4 |
| ICH; tPA complicaiton | – | 10 (3.8) | 0.7 |
| Median mRS (IQR) | 4 (2–5) | 2 (1–4) | 0.4 |
| Persistant AF | 1 (10.0) | 9 (3.4) | 0.06 |
| Paroxysmal AF | 1 (10.0) | 21 (8.0) | 0.3 |
| Smoking | 4 (80.0) | 137 (52.5) | 0.08 |
| MACI | 2 (40.0) | 14 (5.4) | 0.001 |
| STROKE ETIOLOGY | |||
| Atherosclerosis, n (%) | – | 40 (15.3) | 0.6 |
| Cardioembolic | 2 (40.0) | 91 (34.9) | |
| Small-vessel disease | 1 (10.0) | 14 (5.4) | |
| Other | – | 10 (3.8) | |
| Unknown | 2 (40.0) | 105 (40.2) | |
| BLOOD VALUES | |||
| Median D-dimer (IQR), mg/L | 0.6 (0.3–2.8) | 0.7 (0.4–1.6) | 0.9 |
| Mean Hb (SD), g/dL | 12.5 (2.1) | 14.4 (1.4) | 0.002 |
| Mean platelet count (SD), × 109/L | 292.0 (104.7) | 265.9 (78.5) | 0.5 |
| Median fibrinogen (IQR), mmol/L | 3.1 (2.8–4.1) | 3.4 (3.0–3.9) | 0.4 |
| Median CRP (IQR), mg/L | 1 (1–6) | 3 (1–6) | 0.3 |
| Mean cholesterol (SD), mmol/L | 4.1 (1.1) | 5.4 (1.2) | 0.07 |
| Median glucose (IQR), mmol/L | 8.0 (7.1–8.3) | 6.2 (5.4–7.3) | 0.02 |
SD, standard deviation; NIHSS, National Institutes of Health stroke Scale score; IQR, interquartile range; mRS, modified Rankin score; AF, atrial fibrillation; MI, myocardial infarction; PAD, peripheral artery disease; and MACI, multiple acute cerebral infarctions.