Table 2.

Characteristics of the five patients with cancer who received IV-tPA.

	Age, sex	Cancer type	Cancer treatment if prior to stroke	Cancer diagnosis, date	Stroke, date	NIHSS on admission	NIHSS on discharge	Time: ictus to tPA	tPA adverse event	Note
Patient 1: Known cancer	52, male	Colon cancer, lymphnode metastasis	Surgery Oct. 6th 2006. Chemother. from Nov. 17th 2006: (Oxaliplatin + Fluoruracil + Kalsiumfolinat) + Avastin (Bevacizumab)	Sept. 6th 2006	Dec. 8th 2006	13	11	1 h 15 min.	None	Recurrent stroke 2 days later; treated with heparin, no IV-tPA for recurrent stroke.
Patient 2: Occult cancer	77, female	Colon cancer	No treatment pre stroke	Dec. 17th 2007	Dec. 2nd 2007	15	23	2 h 10 min	None	Warfarin seponated 2 weeks prior to stroke due to rectal hemorrhage.
Patient 3: Known cancer	69, male	Malignant melanoma	Surgical resection, July 2010.	July 21st 2010	Nov. 8th 2010	14	19	2 h 31 min.	None	–
Patient 4: Known cancer	62, male	Malignant melanoma	No treatment pre stroke.	Nov. 14th 2010	April 17th 2011	8	0	3 h	None	Died from cancer shortly after stroke. Widespread metastasis.
Patient 5: Occult cancer	77 male	Colon cancer	No treatment pre stroke.	Aug. 29th 2011	July 20th 2011	9	0	1 h 15 min	None	Bladder cancer in 2003. Treated surgically & BCG inj.; full remission.

Bold values represent the NIHSS score as determined by stroke physician, on admission (pre tPA) and on discharge (post tPA).