Table 3.

Sensitivity, specificity, Youden's index, and likelihood ratios for RUDAS and MMSE at different cutoff points (intact cognition vs. MCI + dementia)

	Cutoff point	Sensitivity	Specificity	Youden's index	LR+	LR–
RUDAS	16/17	0.36	0.98	0.34	15.24	0.65
	17/18	0.47	0.98	0.45	19.76	0.54
	18/19	0.51	0.93	0.44	7.14	0.53
	19/20	0.58	0.86	0.44	4.05	0.49
	20/21a	0.66	0.81	0.47	3.45	0.42
	21/22a	0.74	0.74	0.47	2.81	0.36
	22/23b	0.75	0.62	0.36	1.96	0.41
	23/24	0.80	0.55	0.35	1.78	0.36
	24/25	0.90	0.48	0.38	1.72	0.21
MMSE	12/13	0.48	0.90	0.39	5.04	0.57
	13/14a	0.60	0.90	0.50	6.28	0.44
	14/15	0.67	0.81	0.48	3.50	0.41
	15/16	0.69	0.76	0.45	2.88	0.41
	16/17	0.72	0.62	0.33	1.88	0.46
	17/18	0.75	0.57	0.33	1.76	0.43
	18/19	0.79	0.55	0.34	1.76	0.38
	19/20	0.83	0.48	0.31	1.59	0.35
	20/21	0.87	0.38	0.25	1.41	0.33
	21/22	0.91	0.26	0.17	1.24	0.34
	22/23	0.93	0.21	0.15	1.19	0.32
	23/24c	0.94	0.17	0.11	1.13	0.35
	24/25	0.95	0.14	0.09	1.11	0.34

Data based on the comparison between subjects with intact cognition versus patients with MCI + dementia. LR+, positive likelihood ratio; LR-, negative likelihood ratio; Youden's index, (sensitivity + specificity) − 1 [43].

^aBest cutoff score in this study based on Youden's index.

^bRegular cutoff score for RUDAS (Storey et al. [23]).

^cRegular cutoff score for MMSE (Folstein et al. [33]).