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. 2018 Oct;188(10):2392–2405. doi: 10.1016/j.ajpath.2018.06.020

Figure 2.

Figure 2

Expression of kdPKCζ blocks retinal permeability induced by ischemia-reperfusion (IR). C57BL/6J, kdPKCζ, and noncarrier (NC) mice were subjected to retinal ischemia for 90 minutes in the experimental eye, followed by natural reperfusion or sham needle punctured in the contralateral eye. At 48 hours after IR, fluorescein isothiocyanate–conjugated bovine serum albumin (FITC-BSA) assay was used to assess retinal vascular permeability. Results are expressed relative to the C57BL/6J-sham. Statistical analysis was performed using analysis of variance with Tukey's post hoc test. Data are expressed as means ± SEM. ∗P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001.