Table 2.
Allele and genotype risk association analysis of TTTTG-TRIB1 STR with prostate cancer risk.
| Genotype | Cases (%) | Controls (%) | OR (95%CI)a | P-valuea | OR (95% CI)b | P-valueb | P-valuec | P-valued |
|---|---|---|---|---|---|---|---|---|
| 3/3 | 74 (6) | 47 (4) | 1.70 (1.16–2.49) | 0.006 | 1.65 (1.12–2.44) | 0.011 | 0.006 | 0.01 |
| 3/4 | 365 (32) | 384 (31) | 1.03 (0.86–1.23) | 0.75 | – | – | – | – |
| 3/5 | 1 (0.1) | 0 | – | – | – | – | – | – |
| 4/4 | 701 (61) | 759 (63) | 1 | – | – | – | – | |
| 4/5 | 9 (0.7) | 9 (0.7) | – | – | – | – | – | – |
| 5/5 | 2 (0.2) | 0 | – | – | – | – | – | – |
| Allele | ||||||||
| 3 | 514 (22) | 478 (20) | 1.16 (1.00–1.34) | 0.044 | 1.18 (1.01–1.36) | 0.03 | 0.044 | 0.031 |
| 4 | 1776 (77) | 1911 (80) | 0.57 (0.44–0.75) | <0.0001 | 0.59 (0.45–0.77) | <0.0001 | 0.001 | 0.001 |
| 5 | 14 (0.6) | 9 (0.4) | – | – | – | – | – | – |
Calculated using abinary Logistic Regression, where the dependant variable is the case-control status and the covariate is the allele/genotypebage adjusted binary logistic regression, where age is the second covariate cbootstrap (two-tailed) and dbootstrap (two-tailed) age adjusted. (IBM SPSS Statistic Processor; 23). CI, confidence interval; OR, odds ratio.