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. 2018 Aug 31;10(10):e9024. doi: 10.15252/emmm.201809024

Figure EV3. miR‐223 Y/− mice show accelerated Staphylococcus aureus‐infected skin wound healing.

Figure EV3

  • A
    H&E staining of re‐epithelialization at day 7 after injury (wound margin (arrowheads) and the leading edge of epithelia (arrows)). Dotted line indicates pathological necrotic lesion. Scale bars: 500 μm (top) and 100 μm (bottom).
  • B
    Schematic indicating the measurements derived from histological sections.
  • C
    Measurement of the epithelial tongue at day 3 and day 7 after injury in WT (day 3; n = 4, day 7; n = 8) and miR‐223 Y/− (day 3; n = 5, day 7; n = 6) mice.
  • D
    Measurement of the total wound area, necrotic lesion area, and granulation tissue area at day 7 after injury in WT neutrophil‐transplanted and miR‐223 Y/− neutrophil‐transplanted wounds (n = 6).
  • E
    Quantification of the expression of αSMA at day 7 in S. aureus‐infected wound sites from WT (n = 6) and miR‐223 Y/− mice (n = 7).
  • F
    Measurements of the granulation tissue area at day 14 in WT (n = 7) or miR‐223 Y/− wound sites (n = 5).
Data information: All values represent the mean ± SD. Unpaired t‐tests were used to generate P‐values indicated in the Figure. *< 0.05.