Fig. 3. Synthetic mch gene clusters and generated myxochromides. Synthetic mch clusters for production of native (i) and novel hybrid (iii) myxochromides. Abbreviations of the assembled gene cluster fragments are shown on the top. The lowercase letter indicates from which gene cluster type the fragment originates, which is also reflected by coloring (A-type, white; B-type, red; C-type, green; D-type, orange or S-type, blue). Simplified chemical structures of the produced native (ii) and hybrid (iv) myxochromides. The corresponding myxochromide type is indicated on the right; detailed structural information of the novel hybrid types (AS, SA, SB, SC, and SD) is given in ESI section 5.† FA, polyunsaturated fatty acid.
