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. 2018 Oct 8;8(11):303–318. doi: 10.1177/2045125318781475

Table 1.

Response and dropout rates according to different criteria in the antipsychotic-treated and placebo-treated groups as reported in a comprehensive meta-analysis of placebo-controlled antipsychotic drug trials in acute schizophrenia (data from Leucht et al.9).

Outcome % of patients treated with antipsychotic % of patients treated with placebo No. of studies Total sample Number needed to treat to benefit (NNT) (credible interval)
Minimal response 51 30 46 8918 5 (4–5)
Good response 23 14 38 8403 8 (6–11)
Stopping treatment: any reason 38 56 105 22,851 11 (9–14)
Stopping treatment: inefficacy 13 26 94 23,017 7 (6–9)