Table 1.
Characteristics of the patients with different stages of renal disease (CKD chronic kidney disease; ESRD-HD end-stage renal disease treated with hemodialysis; renal transplant: recipients of a renal transplant)
| CKD N = 112 |
ESRD-HD N = 24 |
Renal transplant N = 72 |
P (ANOVA) Kruskal Wallis test | |
|---|---|---|---|---|
| Age | 66 (51, 76) | 63 (50, 76) | 60 (49, 67) | 0.04 |
| Sex (m/f) | 79/33 (71%/29%) | 17/7 (71%/29%) | 51/21 (71%/29%) | 0.999 |
| Body mass index (kg/m2) | 27.4 (23.9, 31.0) | 24.7 (21.8, 27.5) | 26.0 (24.0, 29.3) | 0.02 |
| Hypertension n (%) | 82 (92%) | 23 (96%) | 28 (39%) | < 0.001 |
| Diabetes mellitus n (%) | 33 (30%) | 11 (46%) | 11 (15%) | < 0.001 |
| Current smoking n (%) | 17 (15%) | 3 (12%) | 8 (11%) | 0.104 |
| No. of prescribed medicationa | 7 (4, 9) | 14 (12, 17) | 9 (7, 11) | < 0.001 |
| eGFRb (ml/min/1.73m2) | 28 (18, 38) | 6 (5, 8) | 53 (38, 73) | < 0.001 |
| CKD stages n (1–3/4/5) | 44/52/16 | 0/0/24 | 59/11/1 | |
| Systolic blood pressure (mmHg) | 134 (125, 145) | 159 (142, 175)c | 130 (120, 140) | < 0.001 |
| Diastolic blood pressure (mmHg) | 80 (70, 82) | 67 (61, 77)c | 80 (71, 82) | < 0.001 |
| Years on dialysis | – | 2 (1–4) | – | |
| Years since renal transplant | – | – | 8.9 (5.9, 15.5) | |
| Serum creatinine (μmol/L) | 209 (159, 278) | 656 (560, 844) | 114 (96, 164) | < 0.001 |
| Serum urea (mmol/L) | 16 (11.2, 20.0) | 23 (19, 28) | 9.3 (6.7, 13.8) | < 0.001 |
| Hemoglobin (g/L) | 12.9 ± 1.6 | 11.9 ± 1.6 | 13.6 ± 1.9 | < 0.001 |
| Serum albumin (g/L) | 44 (41, 45) | 40.5 (38, 43) | 43 (41, 45) | 0.001 |
| Serum C-reactive protein (mg/L) | 3 (1, 6) | 3 (1, 16) | 2 (1, 4) | 0.08 |
| HbA1c (%) | 5.8 (5.5, 6.3) | 5.8 ± 1.2 | 5.7 (5.5, 6.1) | 0.12 |
| Urinary albumin (mg/mmol Crea) | 30 (5, 104) | – | 2.7 (0.9, 17.0) | < 0.001 |
aMedication and supplements described in The Norwegian Pharmaceutical Product Compendium (Felleskatalogen AS)
beGFR was calculated using CKD-Epi equation [18]
cpre dialysis, median (IQR)