Fig. 5.

Analyses of differentially expressed genes in morula-blastula-stage embryos. a Venn diagram showing four groups of genes: yellow, genes that were not down-regulated in the NTC group compared to the in vivo group during the morula-blastula period; green, genes that were not down-regulated in the NTM group compared to the in vivo group during the morula-blastula period; blue, genes expressed at higher levels in the NTC blastula than in the in vivo blastula; and red, genes expressed at higher levels in the NTM blastula than in the in vivo blastula. b GO analyses of 1300 key genes selected as described in A. c KEGG analyses of 1300 key genes selected as described in (a). d Detailed description of the differences in the phosphatidylinositol signaling pathway. Red indicates up-regulated transcription when the morula developed to the blastula in each group, whereas blue indicates down-regulated transcription