Fig. 5.

Detection of apoptosis in a Lewis lung carcinoma model. a Apoptosis rates of tumor tissue in different treatment groups were performed by flow cytometry analysis. b Representative histogram showing significant differences of apoptosis rates in different treatment groups. c Expression of Bcl-2, bax, and caspase-3 were determined by Western blot analysis. GAPDH served as the loading control. Data are presented as the mean ± SD. ^*P < 0.05, ^**P < 0.01 versus the control group; ^#P < 0.05, ^##P < 0.01 versus the MET NVB+ Endo group