Table 2.
Comparison of treatment outcomes, ocular complications, and refractive errors.
| Temporal-sparing LIO + IVB | LIO alone | p value | |
|---|---|---|---|
| Early treatment outcome | |||
| Plus sign disappeared (%) | 32 (100) | 42 (100) | |
| Time to plus sign regression (days) | 12.1 ± 6.2 | 25.6 ± 21.3 | 0.011‡ |
| Retreatment (%) | 0 (0) | 10 (23.8) | 0.004† |
| Time to retreatment (days) | 25.0 ± 14.4 | ||
| Retinal/preretinal hmr (%) | 3 (9.4) | 18 (42.9) | 0.002∗ |
| Vitreous hmr (%) | 0 (0) | 4 (9.5) | 0.129† |
| Ocular inflammation (%) | 0 (0) | 0 (0) | |
| Endophthalmitis (%) | 0 (0) | 0 (0) | |
| Adverse systemic safety issues (%) | 0 (0) | 0 (0) | |
|
| |||
| Late complications | |||
| Macular dragging (%) | 0 (0) | 5 (11.9%) | 0.065† |
| Optic disc atrophy (%) | 4 (12.5) | 8 (19.0%) | 0.449∗ |
| Strabismus (%) | 10 (31.3) | 14 (33.3) | 0.850∗ |
| Nystagmus (%) | 6 (18.8) | 6 (14.3) | 0.606∗ |
| Amblyopia (%) | 8 (25.0) | 10 (23.8) | 0.906∗ |
| Cataract (%) | 0 (0) | 0 (0) | |
| Microcornea (%) | 0 (0) | 0 (0) | |
| Angle closure glaucoma (%) | 0 (0) | 0 (0) | |
|
| |||
| Refractive errors | |||
| Measurement period (months) | 9.7 ± 4.2 | 11.0 ± 5.6 | 0.464‡ |
| Spherical equivalent (D) | −0.43 ± 0.58 | −0.94 ± 2.69 | 0.293‡ |
| Emmetropia (%) | 7 (21.9) | 16 (38.0) | 0.130∗ |
| Mild myopia (0–3 D) (%) | 20 (62.5) | 22 (52.4) | |
| Moderate myopia (3–6 D) (%) | 0 (0) | 0 (0) | |
| High myopia (>6 D) (%) | 0 (0) | 2 (4.8) | |
| Hyperopia (%) | 5 (15.6) | 2 (4.8) | |
Continuous variables are shown as mean ± SD; ∗chi-square analysis; †Fisher's exact test; ‡Student's t-test; hmr, haemorrhage.