Fig. 3.

Anion permeability of Panx1 channels. Panx1 currents in podocytes were recorded with different anions in the external solution. A. Representative whole-cell currents of podocytes with chloride (control) or aspartate in the external solution. B. I-V curves illustrating shifts of Panx1 current reversal potentials upon replacement of extracellular chloride with aspartate (n=5 batches of experiments). C. Representative whole-cell currents of podocytes with chloride or gluconate in the external solution. D. I-V curves illustrating shifts of Panx1 current reversal potentials upon replacement of extracellular chloride with gluconate (n=8 batches of experiments). * p<0.05 vs. chloride.