Supplementary Table 5.
Illumina ID | Gene symbol | GLU | HOMAIN | TG | TC | HDL | LDL | GGT | ALT | AST | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1# | 2# | 1# | 2# | 1# | 2# | 1# | 2# | 1# | 2# | 1# | 2# | 1# | 2# | 1# | 2# | 1# | 2# | ||
cg00150500 | HCFC1R1 | 0.492 | 0.736 | 0.290 | 0.433 | 0.020 | 0.545 | 0.008 | 0.027* | 0.505 | 0.516 | 0.000 | 0.005* | 0.107 | 0.132 | 0.006 | 0.057 | 0.792 | 0.668 |
cg00574958 | CTP1A | 0.333 | 0.435 | 0.433 | 0.768 | 0.001 | 0.001* | 0.017 | 0.308 | 0.067 | 0.575 | 0.000 | 0.001* | 0.125 | 0.417 | 0.034 | 0.478 | 0.340 | 0.657 |
cg01067963 | MAPK1 | 0.321 | 0.685 | 0.520 | 0.963 | 0.039 | 0.795 | 0.216 | 0.632 | 0.070 | 0.316 | 0.018 | 0.259 | 0.365 | 0.201 | 0.006 | 0.035* | 0.603 | 0.454 |
cg01693328 | 0.899 | 0.875 | 0.408 | 0.665 | 0.247 | 0.816 | 0.126 | 0.170 | 0.173 | 0.441 | 0.087 | 0.165 | 0.162 | 0.174 | 0.002 | 0.009* | 0.111 | 0.185 | |
cg01801101 | AMZ1 | 0.971 | 0.949 | 0.392 | 0.838 | 0.006 | 0.211 | 0.240 | 0.280 | 0.287 | 0.844 | 0.016 | 0.078 | 0.983 | 0.932 | 0.000 | 0.002* | 0.818 | 0.488 |
cg02013957 | CAGE1 | 0.860 | 0.788 | 0.010 | 0.010* | 0.049 | 0.371 | 0.213 | 0.951 | 0.051 | 0.656 | 0.150 | 0.413 | 0.133 | 0.122 | 0.001 | 0.024* | 0.498 | 0.082 |
cg03511638 | FBXL15 | 0.158 | 0.282 | 0.136 | 0.258 | 0.129 | 0.930 | 0.585 | 0.985 | 0.373 | 0.908 | 0.073 | 0.446 | 0.113 | 0.141 | 0.010 | 0.070 | 0.588 | 0.818 |
cg03615240 | 0.147 | 0.757 | 0.286 | 0.355 | 0.101 | 0.206 | 0.036 | 0.142 | 0.816 | 0.237 | 0.012 | 0.012* | 0.179 | 0.400 | 0.000 | 0.033* | 0.061 | 0.373 | |
cg03992938 | CCDC13 | 0.107 | 0.296 | 0.067 | 0.032* | 0.844 | 0.139 | 0.035 | 0.449 | 0.404 | 0.240 | 0.001 | 0.006* | 0.016 | 0.021* | 0.012 | 0.011* | 0.187 | 0.882 |
cg04160753 | C10orf91 | 0.162 | 0.316 | 0.936 | 0.880 | 0.014 | 0.105 | 0.030 | 0.161 | 0.466 | 0.798 | 0.014 | 0.108 | 0.295 | 0.361 | 0.104 | 0.345 | 0.904 | 0.986 |
cg04787602 | C1orf183 | 0.153 | 0.304 | 0.328 | 0.396 | 0.044 | 0.271 | 0.058 | 0.914 | 0.046 | 0.259 | 0.001 | 0.039* | 0.033 | 0.035* | 0.001 | 0.010* | 0.181 | 0.207 |
cg04981696 | ABCC1 | 0.260 | 0.318 | 0.420 | 0.784 | 0.046 | 0.090 | 0.055 | 0.778 | 0.470 | 0.645 | 0.002 | 0.033* | 0.657 | 0.736 | 0.000 | 0.004* | 0.777 | 0.547 |
cg05102190 | ZYX | 0.116 | 0.122 | 0.972 | 0.880 | 0.039 | 0.084 | 0.056 | 0.360 | 0.301 | 0.926 | 0.025 | 0.077 | 0.338 | 0.365 | 0.005 | 0.030* | 0.812 | 0.717 |
cg05131957 | CRLS1 | 0.091 | 0.199 | 0.489 | 0.876 | 0.032 | 0.274 | 0.068 | 0.312 | 0.585 | 0.892 | 0.006 | 0.047* | 0.995 | 0.780 | 0.018 | 0.069 | 0.483 | 0.196 |
cg05209527 | SLC5A6 | 0.143 | 0.519 | 0.254 | 0.407 | 0.141 | 0.919 | 0.040 | 0.109 | 0.563 | 0.908 | 0.005 | 0.506 | 0.923 | 0.353 | 0.000 | 0.006* | 0.478 | 0.317 |
cg06706068 | RPUSD1 | 0.034 | 0.020* | 0.477 | 0.970 | 0.533 | 0.052 | 0.032 | 0.268 | 0.090 | 0.748 | 0.023 | 0.049* | 0.233 | 0.243 | 0.003 | 0.043* | 0.851 | 0.586 |
cg07067744 | BRSK2 | 0.782 | 0.974 | 0.454 | 0.760 | 0.093 | 0.104 | 0.038 | 0.963 | 0.389 | 0.782 | 0.003 | 0.030* | 0.360 | 0.435 | 0.012 | 0.108 | 0.694 | 0.757 |
cg07112456 | LRWD1 | 0.167 | 0.261 | 0.370 | 0.531 | 0.230 | 0.199 | 0.071 | 0.660 | 0.470 | 0.664 | 0.033 | 0.178 | 0.082 | 0.097 | 0.031 | 0.208 | 0.475 | 0.480 |
cg07953400 | PIGQ | 0.001 | 0.004* | 0.625 | 0.452 | 0.233 | 0.005* | 0.000 | 0.823 | 0.916 | 0.770 | 0.000 | 0.001* | 0.250 | 0.343 | 0.013 | 0.041* | 0.939 | 0.439 |
cg07956264 | GPATCH3 | 0.702 | 0.693 | 0.026 | 0.068 | 0.000 | 0.028* | 0.029 | 0.002* | 0.112 | 0.493 | 0.009 | 0.023* | 0.158 | 0.164 | 0.000 | 0.002* | 0.282 | 0.232 |
cg08013262 | INSR | 0.582 | 0.678 | 0.482 | 0.695 | 0.031 | 0.046* | 0.023 | 0.242 | 0.850 | 0.569 | 0.013 | 0.061 | 0.847 | 0.952 | 0.001 | 0.005* | 0.859 | 0.992 |
cg09367046 | ANGEL1 | 0.275 | 0.356 | 0.557 | 0.793 | 0.109 | 0.351 | 0.190 | 0.811 | 0.203 | 0.624 | 0.022 | 0.118 | 0.175 | 0.205 | 0.000 | 0.002* | 0.198 | 0.188 |
cg10077144 | 0.722 | 0.544 | 0.467 | 0.283 | 0.006 | 0.203 | 0.029 | 0.084 | 0.645 | 0.736 | 0.007 | 0.138 | 0.950 | 0.711 | 0.002 | 0.004* | 0.776 | 0.621 | |
cg10178228 | FRMD4B | 0.566 | 0.705 | 0.482 | 0.603 | 0.447 | 0.937 | 0.668 | 0.196 | 0.005 | 0.055 | 0.078 | 0.357 | 0.240 | 0.270 | 0.000 | 0.005* | 0.838 | 0.776 |
cg12289509 | TUBE1 | 0.402 | 0.503 | 0.479 | 0.670 | 0.236 | 0.029* | 0.019 | 0.921 | 0.676 | 0.683 | 0.001 | 0.002* | 0.443 | 0.489 | 0.000 | 0.001* | 0.624 | 0.833 |
cg12473838 | SSBP1 | 0.004 | 0.167 | 0.500 | 0.711 | 0.419 | 0.928 | 0.000 | 0.192 | 0.000 | 0.664 | 0.001 | 0.030* | 0.122 | 0.140 | 0.755 | 0.199 | 0.453 | 0.765 |
cg13291296 | GPR125 | 0.652 | 0.802 | 0.697 | 0.967 | 0.034 | 0.101 | 0.064 | 0.256 | 0.063 | 0.211 | 0.010 | 0.028* | 0.242 | 0.253 | 0.012 | 0.057 | 0.752 | 0.820 |
cg13397649 | AFG3L2 | 0.090 | 0.227 | 0.678 | 0.749 | 0.003 | 0.809 | 0.305 | 0.079 | 0.133 | 0.385 | 0.038 | 0.295 | 0.898 | 0.948 | 0.017 | 0.082 | 0.301 | 0.156 |
cg13463639 | SIGIRR | 0.082 | 0.551 | 0.618 | 0.985 | 0.376 | 0.709 | 0.002 | 0.348 | 0.028 | 0.363 | 0.009 | 0.020* | 0.375 | 0.275 | 0.980 | 0.730 | 0.298 | 0.431 |
cg13920768 | PRDM12 | 0.278 | 0.431 | 0.539 | 0.635 | 0.004 | 0.101 | 0.035 | 0.065 | 0.855 | 0.221 | 0.016 | 0.095 | 0.278 | 0.347 | 0.007 | 0.040* | 0.779 | 0.710 |
cg14214745 | CRELD1 | 0.764 | 0.627 | 0.141 | 0.246 | 0.001 | 0.419 | 0.207 | 0.024* | 0.022 | 0.196 | 0.048 | 0.218 | 0.883 | 0.713 | 0.041 | 0.267 | 0.314 | 0.359 |
cg14247318 | 0.405 | 0.309 | 0.206 | 0.361 | 0.052 | 0.009* | 0.017 | 0.146 | 0.456 | 0.718 | 0.004 | 0.004* | 0.224 | 0.215 | 0.011 | 0.031* | 0.648 | 0.821 | |
cg14451560 | ARRDC1 | 0.132 | 0.129 | 0.282 | 0.480 | 0.075 | 0.191 | 0.117 | 0.452 | 0.044 | 0.182 | 0.022 | 0.076 | 0.040 | 0.047* | 0.014 | 0.078 | 0.796 | 0.810 |
cg15226170 | PMM1 | 0.894 | 0.780 | 0.422 | 0.625 | 0.024 | 0.354 | 0.136 | 0.352 | 0.511 | 0.911 | 0.012 | 0.095 | 0.302 | 0.203 | 0.001 | 0.009* | 0.535 | 0.537 |
cg15317837 | GTPBP4 | 0.920 | 0.942 | 0.194 | 0.550 | 0.005 | 0.682 | 0.507 | 0.282 | 0.012 | 0.244 | 0.166 | 0.460 | 0.650 | 0.708 | 0.016 | 0.254 | 0.127 | 0.472 |
cg15536552 | ACSL4 | 0.001 | 0.439 | 0.001 | 0.045* | 0.001 | 0.189 | 0.050 | 0.478 | 0.670 | 0.667 | 0.001 | 0.085 | 0.119 | 0.664 | 0.001 | 0.043* | 0.071 | 0.431 |
cg15653194 | LFNG | 0.167 | 0.052 | 0.190 | 0.843 | 0.000 | 0.001* | 0.006 | 0.010* | 0.124 | 0.320 | 0.001 | 0.001* | 0.840 | 0.955 | 0.016 | 0.453 | 0.001 | 0.111 |
cg16105594 | MEF2C | 0.228 | 0.481 | 0.701 | 0.832 | 0.042 | 0.234 | 0.067 | 0.437 | 0.020 | 0.064 | 0.002 | 0.022* | 0.411 | 0.500 | 0.026 | 0.124 | 0.086 | 0.213 |
cg16261091 | HEXDC | 0.722 | 0.620 | 0.073 | 0.146 | 0.005 | 0.315 | 0.242 | 0.110 | 0.093 | 0.465 | 0.044 | 0.118 | 0.097 | 0.095 | 0.004 | 0.036* | 0.561 | 0.614 |
cg16357287 | SEH1L | 0.574 | 0.745 | 0.092 | 0.138 | 0.081 | 0.183 | 0.110 | 0.446 | 0.126 | 0.361 | 0.008 | 0.025* | 0.773 | 0.709 | 0.000 | 0.003* | 0.644 | 0.386 |
cg16398128 | ZNF622 | 0.410 | 0.717 | 0.339 | 0.352 | 0.003 | 0.022* | 0.005 | 0.058 | 0.365 | 0.766 | 0.000 | 0.001* | 0.976 | 0.859 | 0.000 | 0.001* | 0.809 | 0.764 |
cg16416718 | CAMTA1 | 0.001 | 0.004* | 0.739 | 0.772 | 0.200 | 0.010* | 0.001 | 0.778 | 0.387 | 0.558 | 0.000 | 0.001* | 0.053 | 0.069 | 0.031 | 0.079 | 0.984 | 0.313 |
cg16487280 | MYBL2 | 0.082 | 0.070 | 0.708 | 0.744 | 0.183 | 0.112 | 0.064 | 0.488 | 0.989 | 0.067 | 0.006 | 0.027* | 0.671 | 0.497 | 0.081 | 0.624 | 0.004 | 0.060 |
cg17162475 | C6orf150 | 0.317 | 0.328 | 0.201 | 0.465 | 0.052 | 0.507 | 0.341 | 0.874 | 0.052 | 0.618 | 0.032 | 0.165 | 0.562 | 0.635 | 0.000 | 0.008* | 0.611 | 0.313 |
cg17176517 | SNX4 | 0.349 | 0.639 | 0.406 | 0.446 | 0.255 | 0.182 | 0.042 | 0.821 | 0.291 | 0.593 | 0.005 | 0.062 | 0.563 | 0.713 | 0.006 | 0.030* | 0.715 | 0.484 |
cg18570553 | PRR15 | 0.042 | 0.098 | 0.444 | 0.310 | 0.028 | 0.043* | 0.008 | 0.387 | 0.640 | 0.712 | 0.001 | 0.009* | 0.063 | 0.084 | 0.005 | 0.035* | 0.527 | 0.705 |
cg18848688 | LIFR | 0.885 | 0.925 | 0.125 | 0.242 | 0.003 | 0.064 | 0.051 | 0.102 | 0.023 | 0.175 | 0.005 | 0.012* | 0.224 | 0.221 | 0.002 | 0.022* | 0.651 | 0.826 |
cg19189310 | RPS10 | 0.398 | 0.564 | 0.453 | 0.711 | 0.062 | 0.150 | 0.052 | 0.953 | 0.205 | 0.964 | 0.009 | 0.086 | 0.200 | 0.239 | 0.005 | 0.075 | 0.292 | 0.224 |
cg19634213 | PTEN | 0.194 | 0.497 | 0.494 | 0.932 | 0.900 | 0.353 | 0.102 | 0.213 | 0.483 | 0.651 | 0.010 | 0.092 | 0.297 | 0.356 | 0.001 | 0.002* | 0.236 | 0.447 |
cg19878987 | LDHB | 0.321 | 0.532 | 0.328 | 0.574 | 0.086 | 0.136 | 0.034 | 0.691 | 0.477 | 0.932 | 0.008 | 0.087 | 0.176 | 0.240 | 0.001 | 0.003* | 0.197 | 0.218 |
cg21786114 | EHMT2 | 0.344 | 0.374 | 0.953 | 0.367 | 0.023 | 0.073 | 0.060 | 0.841 | 0.363 | 0.484 | 0.004 | 0.029* | 0.600 | 0.654 | 0.001 | 0.018* | 0.809 | 0.483 |
cg22185268 | COMMD4 | 0.943 | 0.744 | 0.548 | 0.618 | 0.007 | 0.180 | 0.058 | 0.108 | 0.299 | 0.842 | 0.001 | 0.019* | 0.329 | 0.431 | 0.001 | 0.008* | 0.467 | 0.844 |
cg22746421 | 0.798 | 0.779 | 0.030 | 0.105 | 0.130 | 0.237 | 0.205 | 0.633 | 0.011 | 0.241 | 0.021 | 0.054 | 0.302 | 0.289 | 0.002 | 0.038* | 0.163 | 0.527 | |
cg23224405 | DUSP16 | 0.873 | 0.594 | 0.099 | 0.062 | 0.024 | 0.256 | 0.053 | 0.351 | 0.099 | 0.194 | 0.002 | 0.054 | 0.147 | 0.199 | 0.000 | 0.001* | 0.197 | 0.435 |
cg24199050 | GTSE1 | 0.064 | 0.175 | 0.949 | 0.862 | 0.012 | 0.006* | 0.001 | 0.129 | 0.719 | 0.984 | 0.000 | 0.001* | 0.754 | 0.988 | 0.004 | 0.013* | 0.717 | 0.190 |
cg24689754 | C19orf62 | 0.357 | 0.466 | 0.273 | 0.341 | 0.147 | 0.607 | 0.366 | 0.576 | 0.102 | 0.183 | 0.007 | 0.045* | 0.731 | 0.593 | 0.001 | 0.005* | 0.368 | 0.104 |
cg25295726 | FUT11 | 0.685 | 0.906 | 0.175 | 0.314 | 0.056 | 0.231 | 0.094 | 0.748 | 0.030 | 0.184 | 0.007 | 0.050 | 0.112 | 0.130 | 0.003 | 0.040* | 0.699 | 0.746 |
cg25456633 | 0.613 | 0.938 | 0.003 | 0.003* | 0.080 | 0.581 | 0.235 | 0.649 | 0.296 | 0.688 | 0.085 | 0.377 | 0.626 | 0.742 | 0.001 | 0.012* | 0.893 | 0.758 | |
cg25818813 | MERTK | 0.131 | 0.253 | 0.968 | 0.926 | 0.087 | 0.037* | 0.015 | 0.264 | 0.848 | 0.545 | 0.000 | 0.002* | 0.478 | 0.550 | 0.000 | 0.001* | 0.179 | 0.513 |
cg26105057 | PAN2 | 0.843 | 0.972 | 0.305 | 0.831 | 0.029 | 0.122 | 0.161 | 0.401 | 0.107 | 0.656 | 0.058 | 0.082 | 0.155 | 0.137 | 0.000 | 0.002* | 0.522 | 0.167 |
cg26309655 | TARS2 | 0.103 | 0.299 | 0.820 | 0.667 | 0.065 | 0.172 | 0.032 | 0.301 | 0.671 | 0.670 | 0.006 | 0.077 | 0.391 | 0.514 | 0.004 | 0.008* | 0.757 | 0.542 |
g22721468 | SH3BP5L | 0.097 | 0.225 | 0.616 | 0.649 | 0.232 | 0.106 | 0.028 | 0.816 | 0.618 | 0.787 | 0.000 | 0.009* | 0.465 | 0.569 | 0.001 | 0.008* | 0.643 | 0.882 |
1# – Uni-variate p; 2# – Multi-variate; p* p<0.05, adjusted by sex, age and BMI.