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Diagnostic value of anti-dsDNA isotypes and anti-c1q antibody for lupus nephritis.
| Sensitivity | Specificity | PPV | NPV | OR (95% CI) | |
|---|---|---|---|---|---|
| Anti-C1q | 59% | 63% | 64% | 58% | 2.407 (1.001–5.793) |
| Anti-dsDNA IgM negative | 70% | 59% | 69% | 64% | 3.316 (1.427–7.702) |
| Anti-C1q positive and anti-dsDNA IgM negative | 34% | 96% | 90% | 57% | 11.333 (2.446–52.502) |
SLE: systemic lupus erythematosus; PPV: positive predictive value; NPV: negative predictive value; OR: odds ratio; CI: confidence interval.
