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Schematic model illustrating the proposed role of GhCPK33 in plant defense against V. dahliae. GhCPK33 negatively regulates plant defense against V. dahliae via phosphorylating GhOPR3 to block JA biosynthesis. Knocking down the expression level of GhCPK33 results in the accumulation of JA and JA-Ile and constitutively activates the JA-mediated defense response, enhancing plant resistance to V. dahliae. +P, Phosphorylation.
