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. 2018 Oct 8;13:6177–6188. doi: 10.2147/IJN.S176404

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© 2018 Zheng et al. This work is published and licensed by Dove Medical Press Limited

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(A) Representative in vivo MRI and (B) Masson-stained tissue section of the infarcted heart with the administration of MnO-PEG-Cy5.5 nanoparticles by tail vein injection. (C) CNR of remote vs. infarcted myocardium of three rats during the first 90 minutes after MnO-PEG-Cy5.5 nanoparticles injection. Data are expressed as means ± SD.

Note: Yellow circles indicate the hypoenhancement of the infarcted myocardium.

Abbreviations: CNR, contrast-to-noise ratio; MI, myocardial infarction; MRI, magnetic resonance imaging.