Table 1.

Model statistics for Discovery Studio Bayesian Models for Kinase Selectivity A. training set B test set minus overlapping compounds in Ambit.

A. Training set
5-Fold Cross-Validation Result
Model Name	ROC Score	ROC Rating	True Positive	False Negative	False Positive	True Negative	Sensitivity	Specificity	Concordance
kinase selectivity and Ambit minus overlap	0.858	Good	941	167	37	352	0.849	0.905	0.864
A. Test Set
Validation Result Using External Test Set AmbitDataMinusOverlap.sd
Model Name	ROC Score	ROC Rating	True Positive	False Negative	False Positive	True Negative	Sensitivity	Specificity	Concordance
kinase selectivity and Ambit minus overlap	0.813	Good	44	7	6	11	0.863	0.647	0.809