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. Author manuscript; available in PMC: 2019 Jan 5.
Published in final edited form as: ACS Catal. 2017 Nov 22;8(1):59–62. doi: 10.1021/acscatal.7b03323

Figure 1.

Figure 1

7IY forms amyloid-like fibrils that catalyze paraoxon hydrolysis. a) AFM images of the fibrils formed by 7IY in the presence of CuII; peptides were incubated for 15–30 min prior to deposition onto mica; b) CD spectra of 7IY under various conditions ([7IY] = [CuII]= 25 μM, 5 mM HEPES, pH 8.0); c) dependence of initial rate of paraoxon hydrolysis catalyzed by 7IY on the substrate concentration; peptides were incubated at 37 °C for 30 min prior to addition of substrate to ensure fibril formation.