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. 2018 Oct 11;13(10):e0204688. doi: 10.1371/journal.pone.0204688

Fig 2. Three TF combinations induce pyramidal-shaped neurons morphologically resembling adult human cortical neurons.

Fig 2

(A) Bar diagrams illustrating soma size (top) and pyramidal morphology index (PMI, left) of hES-iNs compared to hFCtxC and hACtxC cells. Mean±SEM (n = 3); *, p<0.05, one-way ANOVA. (B) Tracing showing the pyramidal shape and complex morphology of the hES-iNs at 8 weeks in culture, different from the hFCtxC cells but resembling that of hACtxC cells. Scale bar = 20 μm; n corresponds to a number of independent differentiation experiments.