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. 2018 Oct 11;13(10):e0205398. doi: 10.1371/journal.pone.0205398

Table 1. Characteristics of patients diagnosed with pulmonary tuberculosis and their asymptomatic household contacts.

Active TB Disease
(n = 17)
Household
Contacts (n = 16)
P-valuec
Age [years; median (IQR)]a 27 (24–42) 35 (29–48) 0.05
Male sex, n (%) 10 (59%) 6 (38%) 0.22
Tobacco use 13 (76%) 6 (38%) 0.02
High grade AFB sputum smeara 1 (6%) N/A N/A
>100 Colonies on semi-quantitative culture 7 (41%) N/A N/A
Cavitation on chest radiograph 2 (12%) N/A N/A
Multidrug-resistant TBb 3 (18%) N/A N/A

IQR, interquartile range; AFB, acid-fast bacilli; TB, tuberculosis.

a. Sputum smear and culture obtained at study enrollment; high grade smear defined as > 1 AFB per high power field

b. Multidrug resistance was defined as resistance to both isoniazid and rifampin by drug susceptibility testing

c. A Wilcoxon rank sum test was used for comparisons of continuous data and a two-tailed Fisher exact test was used for categorical data