Fig 5. CPB elicits a systemic innate cytokine response.
A significant increase in the concentration IL-1b (A) and IL-6 (B) in plasma was observed post-CPB compared to control. P< 0.05. n = 8 mice per group. Plasma concentrations of T-cell regulatory cytokines IL-2 (D), IL-13 (E), GM-CSF (F), IL12p40 (G),IL12p70 (H), IL-17 (I), IFNgamma (J) and IL-10 (K). All values were corrected for hemodilution.