Table 2. Relationship between serum periostin and disease activity in eosinophilic granulomatosis with polyangiitis.

Outcome	Exposure	Univariate analysis odds ratio or beta-coefficient (95% CI) p-value	Multivariate analysis odds ratio or beta-coefficient (95% CI) p-value
Flare visit (yes vs no)	Periostin level	OR 1.00 (0.99 to 1.02) p = 0.42	OR 1.00 (0.98 to 1.02) p = 0.98
	Change in periostin level	OR 0.99 (0.97 to 1.01) p = 0.30	OR 0.99 (0.97 to 1.01) p = 0.15
	Percent change in periostin level	OR 0.70 (0.17 to 2.91) p = 0.62	OR 0.43 (0.09 to 2.14) p = 0.30
Physician Global Assessment Score	Periostin level	beta 0.01 (0.002 to 0.02) p = 0.01	beta 0.02 (0.004 to 0.03) p = 0.01
	Change in periostin level	beta 0.01 (-0.002 to 0.02) p = 0.12	beta 0.01 (-0.005 to 0.02) p = 0.26
	Percent change in periostin level	beta 0.55 (-0.39 to 1.48) p = 0.25	beta 0.41 (-0.56 to 1.39) p = 0.40

Multivariate analyses adjusted for ANCA type (ever positive or not), active asthma in the past 28 days, current prednisone use, and current use of other immunosuppressive therapies; for all analyses except percent change in periostin level, baseline periostin also included in model.

CI, confidence interval. OR, odds ratio.