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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Comput Biol Med. 2018 Jul 7;100:209–220. doi: 10.1016/j.compbiomed.2018.07.004

Figure 1.

Figure 1.

Information flow for the spatial validation of the parametric structured meshes (PSM) against original MRA images as a reference. (Step 1) Cerebrovascular trees are reconstructed from MRA using PSM method. (Step 2) MRA and PSM reconstruction are superimposed in a virtual reality environment Walk-in Brain. Vascular segments and bifurcations are scanned and 2D sampling frames are automatically acquired. (Step 3) Spatial accuracy evaluation between PSM with original MRA images by correlating lumen area, pixel-based statistical analysis, area overlap measurements and centerline accuracy measurements. (Step 4) Applications of PSM meshes; examples include cerebrovascular morphometric analysis of image databases of patients and subject-specific hemodynamic simulation of the entire arterial circulation.