Table 3.
Physical Function: Odds or Poorer Physical Function According to Individual Characteristics of Weight Trajectory
| SPPB Score Category N=1323 |
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|---|---|---|---|---|---|---|
| GOOD (SPPB 10–12, referent) n=331 (25.0) | ||||||
| POOR SPPB 0–3 n=262 (19.8) |
LOW INTERMEDIATE SPPB 4–6 n=344 (26.0) |
HIGH INTERMEDIATE SPPB 7–9 n=386 (29.2) |
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| Weight measurea | Age, clinic adjusted OR (95% CI) |
MV adjustede OR (95% CI) |
Age, clinic adjusted OR (95% CI) |
MV adjustede OR (95% CI) |
Age, clinic adjusted OR (95% CI) |
MV adjustede OR (95% CI) |
| Weight change baseline to Year 20b | ||||||
| No weight loss | 1.0(ref) | 1.0(ref) | 1.0(ref) | 1.0(ref) | 1.0(ref) | 1.0(ref) |
| Minimal weight loss | 1.27 (0.85, 1.89) | 1.54 (0.96, 2.47) | 1.21 (0.85, 1.72) | 1.40(0.93, 2.10) | 1.20 (0.86, 1.68) | 1.34 (0.93, 1.93) |
| Moderate weight loss | 3.20 (1.82, 5.59) | 3.60 (1.86, 6.95) | 2.43 (1.43, 4.14) | 2.52 (1.38, 4.61) | 1.14 (0.65, 2.00) | 1.21 (0.66, 2.21) |
| Abrupt weight declinec | ||||||
| No | 1.0(ref) | 1.0(ref) | 1.0(ref) | 1.0(ref) | 1.0(ref) | 1.0(ref) |
| Yes | 1.20 (0.81, 1.76) | 1.21 (0.80, 1.83) | 1.47 (1.03, 2.08) | 1.37 (0.95, 1.99) | 1.10 (0.78, 1.56) | 1.07 (0.75, 1.53) |
| Weight variability (RMSPE) quartiled | ||||||
| Q1 | 1.0(ref) | 1.0(ref) | 1.0(ref) | 1.0(ref) | 1.0(ref) | 1.0(ref) |
| Q2 | 0.84 (0.51, 1.39) | 0.83 (0.48, 1.43) | 1.09 (0.71, 1.66) | 1.09 (0.69, 1.71) | 1.28 (0.86, 1.92) | 1.32 (0.87, 1.99) |
| Q3 | 1.42 (0.89, 2.29) | 1.22 (0.73, 2.04) | 1.10 (0.71, 1.69) | 0.89 (0.56, 1.42) | 1.27 (0.84, 1.91) | 1.17 (0.76, 1.79) |
| Q4 | 2.69 (1.67, 4.32) | 2.26 (1.34, 3.8) | 1.77 (1.14, 2.76) | 1.56 (0.97, 2.5) | 1.45 (0.94, 2.25) | 1.39 (0.88, 2.19) |
Each model includes only the weight measure of interest and the non-weight covariates.
Categories are relative to population change SD (8.99 kg); no weight loss signifies weight change >=0; minimal weight loss indicates weight change was <=1 SD but <0; moderate weight loss indicates weight change was >1 SD.
Presence of an unrecovered abrupt decline in weight based on whether the weight trajectory fit a quadratic equation with a relative maximum and weight loss continued to the end of weight trajectory (yes/no).
Variability of weight calculated using the root mean square percentage error (RMSPE) of the estimated linear and quadratic weight curves for each woman.
Includes age, clinic, baseline height, Year 20 weight, comorbidity score, self-reported health, and depression.