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. 2018 Oct 11;8:15138. doi: 10.1038/s41598-018-33463-2

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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A selected mid-brain slice from an in-vivo three-dimensional data set is depicted. In (a) the obtained sampling in the three-dimensional acquisition parameter space is shown together with three potential cuts to visualize the data content. These cuts are sub sampled to facilitate the illustration. (b) The TI-b plane at second echo time and (c) the TE-TI plane at b = 0, (d) the TE-b plane at longest TI, are depicted.