Table 2.

Effect sizes for rs699947, rs833070, and rs2146323 SNP effect on psychopathology and cognition in probands and control subjects

	NC						Probands
	rs699947 (GG vs. T-)		rs833070 (GG vs. A-)		rs2146323 (CC vs. A-)		rs699947 (GG vs. T-)		rs833070 (GG vs. A-)		rs2146323 (CC vs. A-)
Psychopathology	p value	Cohen’s d	p value	Cohen’s d	p value	Cohen’s d	p value	Cohen’s d	p value	Cohen’s d	p value	Cohen’s d
Positive total	—	—	—	—	—	—	0.873	0.015	0.728	0.032	0.396	0.079
Delusions	—	—	—	—	—	—	0.615	−0.049	0.649	−0.043	0.931	0.009
Hallucinations	—	—	—	—	—	—	0.109	0.157	0.059	0.176	0.035	0.194
Cognition	p value	Cohen’s d	p value	Cohen’s d	p value	Cohen’s d	p value	Cohen’s d	p value	Cohen’s d	p value	Cohen’s d
Composite	0.210	−0.224	0.427	−0.146	0.198	−0.249	0.727	−0.033	0.675	−0.038	0.559	−0.053
Verbal Memory	0.998	0.020	0.578	−0.106	0.234	−0.219	0.072	−0.167	0.140	−0.135	0.23	−0.109
Digit Sequence	0.213	−0.218	0.453	−0.146	0.108	−0.299	1.000	−0.007	0.904	−0.011	0.994	0.000
Tower of London	0.093	−0.326	0.371	−0.164	0.298	−0.221	0.284	−0.103	0.599	−0.049	0.741	−0.030
Symbol Coding	0.565	−0.109	0.468	−0.129	0.150	−0.269	0.637	0.046	0.649	−0.039	0.519	–0.059

Psychopathology, PANSS (Positive and Negative Syndrome Scale); Cognition, BACS (Brief Assessment of Cognition); for psychopathology measures covaried for age, sex, site, and ethnicity. Adjusted cognition measures were covaried for site and ethnicity

HC healthy control

The bolded values stand for signficant uncorreted p values (p < 0.05)