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. 2018 Oct 11;9:4215. doi: 10.1038/s41467-018-06659-3

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 8 — Antimicrobial peptides and Cg-EcSOD expression is repressed in the susceptible S_F11 oysters. Time-course of antimicrobial peptide (AMP) and Cg-EcSOD expression in S_F11 and R_F21 oysters during the ‘natural’ experimental infection. The relative expression of AMPs was analysed by comparing the number of reads (calculated by alignment using DIAMOND 0.7.9) between each time point and time zero. Analyses were performed using the RNA-seq data by mapping against the C. gigas genome for Cg-EcSOD. The intensity of the colour from blue to yellow indicates the magnitude of the differential expression (log2 fold change). The heatmap was constructed with Multiple Array Viewer software