Table 2.

List of the top 20 most significant GO terms for the target genes found to be differentially expressed in DM-Exos vs. N-Exos and their corresponding annotation for Biological process (BP).

GO ID	Term	P value
GO: 0045471	Response to ethanol	5.30-E-05
GO: 0042593	Glucose homeostasis	0.00016
GO: 0045616	Regulation of keratinocyte differentiation	0.00018
GO: 0051150	Regulation of smooth muscle cell differentiation	0.00025
GO: 0060017	Parathyroid gland development	0.00048
GO: 0007219	Notch signaling pathway	0.00054
GO: 0060560	Developmental growth involved in morphogenesis	0.00056
GO: 0043406	Positive regulation of MAP kinase activity	0.00073
GO: 0007157	Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	0.00075
GO: 0000083	Regulation of transcription involved in G1/S transition of mitotic cell cycle	0.00096
GO: 0051897	Positive regulation of protein kinase B signaling	0.00098
GO: 0030261	Chromosome condensation	0.00121
GO: 0001843	Neural tube closure	0.00124
GO: 0021846	Cell proliferation in forebrain	0.00138
GO: 0050680	Negative regulation of epithelial cell proliferation	0.00149
GO: 0005979	Regulation of glycogen biosynthetic process	0.00151
GO: 0001755	Neural crest cell migration	0.00154
GO: 0045598	Regulation of fat cell differentiation	0.0017
GO: 0000077	DNA damage checkpoint	0.00176
GO: 0050714	Positive regulation of protein secretion	0.00177