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. 2018 Sep 17;3:66. doi: 10.21037/tgh.2018.09.03

Table 2. Summary of studies reported outcomes of ALPPS vs. TSH.

Type of study Ratti et al., 2015 (42) Adam et al., 2016 (4) Sandström et al., 2018 (43)
Retrospective, case-matched Retrospective, case-matched RCT
ALPPS TSH P ALPPS TSH P ALPPS TSH P
No. of cases 12 36 17 41 48 49
Increase in FLR vol. (%) 47 41 NS NR NR 68 36 <0.0001
Median interval (days) 11 31 0.024 12 103 <0.001 11 43 <0.0001
Morbidity (no.) 10 13 0.011 7 16 0.99 19/44 12/28 0.99
90-day mortality NR NR 0 2 0.89 4 3 0.68
Median follow-up 12 37 20 30
Recurrence NR NR 8 17 0.28
Overall survival 92 94 NR 42 77 0.006

ALPPS, associating liver partition and portal vein ligation in staged hepatectomy; TSH, two-stage hepatectomy; NR, not report; RCT, randomized clinical trial.