Skip to main content
. 2018 Oct 5;9:1422. doi: 10.3389/fphys.2018.01422

FIGURE 1.

FIGURE 1

miR-122 regulates SCD expression by binding with 6-nucleotide sequence in SCD 3′-UTR. (A) Sequence complementarity between miR-122 and SCD 3’-UTR. (B) Dual luciferase reporter assay system used to test binding between miR-122 and SCD in HEK293T cells. Ctrl mimic, 3′-UTR wt, 3′-UTR mutant, and miR mimic are also referred to as miRNA negative control, SCD-WT, SCD-Mut, and miR-122 mimic, respectively. Different lowercase letters show significant differences among treatments at each sampling point (P < 0.05, Duncan’s multiple range test).