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. 2018 Oct 5;9:1422. doi: 10.3389/fphys.2018.01422

FIGURE 3.

FIGURE 3

Effect of inhibition of miR-122 on hepatic SCD expression in GIFT. Juvenile GIFT weighing about 3.8 g were injected in tail vein with PBS, miR-122 negative control, or miR-122 antagomir (dose, 50 mg kg-1 body weight) every 6 days for 40 days. GIFT injected with PBS served as control. (A) The expression of miR-122 in liver was detected on days 0, 10, 20, and 40 using qRT-PCR, with U6 as the reference gene. (B) The expression of SCD in liver was detected on days 0, 10, 20, and 40 using qRT-PCR, with 18S rRNA as the reference gene. ∗P < 0.05 indicates significant differences in each group among sampling points (paired-samples t test). The data were expressed as the relative change compared with the control group on day 0. Different lowercase letters show significant differences among treatments at each sampling point (P < 0.05, Duncan’s multiple range test).