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. 2018 Aug 8;46(18):9805–9815. doi: 10.1093/nar/gky702

Figure 1.

Figure 1.

Crystal structure of Streptococcus pyogenes type II-A Cas2. (A) Protomer structure of S. pyogenes type II-A Cas2. Secondary structure elements are also indicated. (B) Dimeric structure of S. pyogenes type II-A Cas2. The 2mFobs − DFcalc map is contoured at 1.0 σ for residues at the interface. (C) Side-by side comparison of S. pyogenes and Enterococcus faecalis type II-A Cas2 structures. The C-terminal tails (residues 92–109) of E. faecalis Cas2 dimer are removed for clarity. (D) Structural alignment of S. pyogenes and E. faecalis type II-A Cas2 dimers based on only one of the two protomers. Note that the ∼43° rigid-body rotation between the two unaligned protomers.